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Luxembourgbased pay TV operator M7 Group has cons

first_imgLuxembourg-based pay TV operator M7 Group has consolidated its M77 Group sister company, bringing the pair’s Belgian, Dutch, Austrian and Czech operations under a single ownership structure.The merger creates a single ownership structure for pay TV operations CanalDigitaal in the Netherlands, TV Vlaanderen and TéléSat in Belgium, Austria’s AustriaSAT, and Skylink and CS Link in the Czech Republic.last_img

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French service provider SFR has named François Rub

first_imgFrench service provider SFR has named François Rubichon as executive director for human resources, general affairs and corporate organisation.Rubichon, who was previously deputy director-general for Aéroports de Paris, will join the SFR executive committee headed by CEO Jean-Yves Charlier.last_img

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Survey Finds Most Police Officers Support Medical Marijuana

first_img Next Article Image credit: Luke Sharrett | Bloomberg | Getty Images Each week hear inspiring stories of business owners who have taken the cannabis challenge and are now navigating the exciting but unpredictable Green Rush. Opinions expressed by Entrepreneur contributors are their own. Easy Search. Quality Finds. Your partner and digital portal for the cannabis community. Add to Queue Survey Finds Most Police Officers Support Medical Marijuana In a sign of the continuing shift in attitudes about legal marijuana, a new survey finds that a majority of police officers now favor allowing the use of medical marijuana.However, the number drops significantly when it comes to the legalization of marijuana for personal use. And one-third of officers surveyed said they still support an outright ban on the use of marijuana for any purpose.Pew Research released the information recently as part of a survey of police officers on a number of issues.Medical marijuana is now legal in 28 states and the District of Columbia. Eight states have legalized marijuana for recreational use: Alaska, California, Colorado, Maine, Massachusetts, Nevada, Oregon and Washington.For those thinking of investing into marijuana businesses, the survey provides a glimpse into how law enforcement might battle any new legalization efforts. Despite being legal under state laws for a majority of the US population, marijuana remains an illegal drug under federal law.Related: 5 Tips for Breaking Into the ‘Budding’ Marijuana IndustryPolice officer surveyThe survey found that, overall, about seven in 10 officers think marijuana should be legalized for at least medical use. The numbers were as follows:37 percent of police officers supported legalizing marijuana for medical use32 percent of police officers supported legalizing marijuana for both personal and medical use30 percent of police officers support a ban on marijuana for any useYounger officers took a more favorable view toward marijuana, with 37 percent saying they support both medical and recreational marijuana.Related: How Cannabis Ecommerce Challenges Are Driving Web InnovationGeneral public surveyWhile the trend toward supporting legalization among law enforcement officers reflects what has happened with voters across the country, the numbers for law enforcement remain below that for the general public.In the same study, Pew reported the following numbers on the same questions asked of adults who do not work in law enforcement. The findings:35 percent supported legalizing marijuana for medical use49 percent supported legalizing marijuana for both medical and personal use15 percent supported a ban on marijuana for any use63 percent of those under the age of 45 support legal marijuana for both personal and medical usePew conducted the study between May and August 2016. They interviewed 7,900 officers in both police and sheriff’s departments. Each department had at least 100 officers. For the general public portion of the survey, Pew interviewed 4,500 adults in August and September of 2016.Related: 4 Cannabis Business Ideas from the Frontier of the Legal Weed IndustryWhile law enforcement attitudes toward legalizing marijuana seems to have relaxed, the nation’s top justice officials have not changed their stance on marijuana as an illegal drug. The U.S. Drug Enforcement Agency had two chances to review petitions on the legal status of marijuana in the summer of 2016. However, DEA officials decided not to make any changes.To stay up to date on the latest marijuana related news make sure to like dispensaries.com on Facebook. Guest Writer Green Entrepreneur Podcast February 9, 2017 3 min read Cannabis Softening attitudes among police lags general public acceptance but seems to confirm an inexorable social trend. Listen Now –shares dispensaries.comlast_img read more

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Instagram Admitting a War on Snapchat Rolls Out Face Filters

first_img With yesterday’s arrival of Instagram Face Filters, Facebook and Instagram’s complete and utter dismantling of the Snapchat platform is complete.Instagram is rolling out eight inaugural Face Filters, including furry koala ears, math equations swirling around your head and — most fittingly — an ice crown. To the winner go the spoils.Not five minutes after Instagram announced Face Filters and several other new features — including a Rewind button, Hashtag stickers and an Eraser button — Instagram VP of Product Kevin Weil walked onstage at TechCrunch Disrupt in New York City shooting an Instagram Story of the crowd.Weil, the former VP of product at Twitter, has been at Instagram for around 15 months. In that time, the app has switched to an algorithmic feed and rolled out Instagram Stories, which now eclipses Snapchat with more than 200 million daily active users (DAUs) in less than a year. Instagram is also testing location-based Stories (like Snapchat’s geofilters and local stories), but hasn’t yet publicly confirmed that feature.”Face filters are an expected part of a modern camera, so we’re super excited to launch them today,” Weil said. “The first eight filters are live now, and we’ve also launched a handful of other things including a reverse video format, a hashtag sticker allowing you to tag stories the same way you can tag mentions and some other tools like an eraser.”The next question, inevitably, is how Instagram’s Face Filters are different from Snapchat’s. You can get to the filters from the face icon in the right corner of the Instagram app when you’re filming a story. Just like Snapchat, you tap a filter to try it on and there are individual and group filters to use with friends in the frame. Face Filters also integrate with Boomerang by default, and the finished snaps ‘grams can be sent as an Instagram DM or uploaded to your story.”The important thing to us when we launched Face Filters was to do it in a way that was natural to Instagram. There’s a level of craft and attention to detail with each of the eight filters that I think is unique,” Weil said. “One of my favorites is the koala filter. I have 7-month-old twins, I put them on screen and I see two little koalas looking up at me, and the ears twitch the same way a koala’s ears naturally twitch. There’s another feature with a spotlight. As you move around, the spotlight will follow you.”These updates are available as part of Instagram version 10.21 for iOS in the Apple App Store and for Android in Google Play.Instagram admits all-out war on Snapchat.Face Filters are the cherry on top of one of the more deft and almost impressively brazen business moves Mark Zuckerberg has made to get Facebook where it is today.Instagram Stories and now Face Filters are one facet of the strategy. Add that to Facebook’s copycat Messenger Day feature and most importantly, the company’s new Camera Effects augmented reality (AR) developer platform announced at F8, and it amounts to a ruthlessly effective scorched earth copycat campaign. Zuckerberg’s F8 keynote was one long subtweet of Snap Inc., where Zuck didn’t mention the word Snapchat once. Today, he also posted an Instagram video in which he sported one of the app’s new filters and congratulated his team on a “nice job.”That’s not the most important part, though. Facebook has also improved upon every core Snapchat feature, adding features and user experience (UX) polish and opening the camera platform to developers in addition to an active user base with which Snapchat can’t compete. During his TechCrunch Disrupt interview, Weil reluctantly acknowledged that Instagram’s strategy around stories and filters was inspired by and came at the expense of Snapchat.”If we’re being honest with ourselves, this is the way the tech industry and frankly all industries work. Good ideas start out in one place and spread all across the industry,” he said. “Kudos to Snapchat for being the first to stories, but it’s a format and it’s going to be adopted across a wide array of platforms.”Weil likened it to Facebook coming up with the News Feed or Twitter pioneering hashtags, both of which are now widely adopted across apps and social networks. In the same vein, he also drew an interesting parallel with the animation world. Pixar was the first to do computer-animated films, but Weil made the point that just because Pixar was first, we shouldn’t discount all the great films made by a studio like DreamWorks.”It’s not just about the format, it’s about the plot. The storyline. It’s the entire product. It’s not just Instagram Stories, it’s the Instagram feed. Raw moments. Direct, where you’re sharing privately. Instagram Live, where you’re taking people with you throughout the day. It would be silly of us to see a good idea and say that because one person did it we can’t even go near it,” Weil said.To interviewer Josh Constine’s credit, he didn’t let up. Most of Instagram’s product development over the past year and a half has been around features Snapchat has already built. Weil became visibly uncomfortable when faced with question after question about whether it’s honorable to copy other products, what the atmosphere was like after Snap Inc. lost 25 percent of its value following its most recent earnings report, and whether the ends justify the means.”There will be multiple successful players in the industry,” Weil responded. “It’s not about one player going down. It’s about building things of value and asking whether you’re closer to the people in your life because of Instagram.” Add to Queue Associate Features Editor Instagram, Admitting a War on Snapchat, Rolls Out Face Filters Next Article This story originally appeared on PCMag 2019 Entrepreneur 360 List Rob Marvincenter_img Instagram’s VP of product dishes on the app’s Face Filters, Hashtag stickers, and Rewind button at TechCrunch Disrupt while fielding a barrage of questions about Snapchat. Image credit: via PC Mag The only list that measures privately-held company performance across multiple dimensions—not just revenue. Instagram –shares Apply Now »last_img read more

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Will Medical Cannabis Sales Eventually Surpass Recreational Sales

first_imgMedical Marijuana 7 min read Image credit: LPETTET | Getty Images Contributor Will Medical Cannabis Sales Eventually Surpass Recreational Sales? Subscribe Now Many assume the recreational marijuana market will surpass medical cannabis but there are many reasons to suspect they will be proved wrong. Medical marijuana could become the bigger of the two within a few years thanks to three factors.Here’s what entrepreneurs should know about the difference between these two markets, and how the cannabis industry’s astronomical growth could evolve differently than one might expect.The current state of the cannabis market.Global cannabis sales reached a new high of $12.2 billion in 2018, up from $9.5 billion in 2017, according to a report by BDS Analytics. More than half of that was recreational. Some examples:Colorado: Out of total revenue of almost $1.55 billion, according to the Colorado Department of Revenue, only $332 million was medical cannabis.California: Sales reached approximately $1.2 billion per state data, more than half of which was recreational.Canada: Statistics Canada reported total sales for October through December reached $115 million USD. At the same time, the number of medical marijuana patients grew in Canada.Sales in US states that have legalized weed appear to be moving away from medical cannabis and towards recreational, though this has not held true in Canada, though there are indications it will once the market matures and there is wider accessibility.Related: Move Aside, CBD: New Data Finds THC Is the Real Medicine in Medical MarijuanaIn the U.S., the legalization of recreational weed has meant a corresponding decline or stagnation in medical cannabis sales. This makes sense for a few reasons. Depending on the state, obtaining a medical marijuana card can be complicated with few doctors willing to prescribe and applications, and medical marijuana patients sometimes must pay a fee.In California, the biggest cannabis market to date, lenient laws created an artificially large medical marijuana market. Today, many of those patients are switching to recreational.The rise of recreational weed has lead to some panic about the future of medical marijuana. Will producers entirely shift their focus away from medical marijuana and to focus on the hottest cannabis products like concentrates vapes, and other high-THC options? Will patients have access to the product they need for target-specific conditions, rather than get you high?There are a few reasons why this will not happen.CBD will be bigger than recreational weed.The recreational market isn’t just booming because people want concentrated THC. In fact, the products with the biggest sales increase in 2018 were high in CBD. The growing interest in medicinal and medical cannabis is a strong indication CBD market will explode in the upcoming years.CBD, also known as cannabidiol, is a compound in cannabis that does not produce a high. ThoughCBD is the second-most popular compound found in weed after THC, it can be found in hemp, too, which is non-psychoactive. This means that it cannot produce unwanted effects, by law.CBD can address a variety of conditions ranging from the severe to the preventative according to a growing body of research and anecdotal evidence. These include both physical conditions including seizures, pain, Alzheimer’s and Parkinson’s disease and mental health issues such as depression and anxiety. CBD provides a much-needed, non-addictive alternative without negative side effects for pain management and epilepsy These conditions afflict millions of Americans who don’t yet use medical marijuana. The potential market is enormous for all-natural products that can address these ailments.CBD edible sales grew astronomically in 2018. In one year alone CBD gummy sales went up 925 percent, sales of CBD chocolate market increased by 530 percent and CBD tincture, also known as cannabis oil, sales went up 111.5 percent.Most predict that the CBD market will eclipse the recreational cannabis market — something that couldn’t have been predicted at the beginning of the legalization movement. The most optimistic projection comes from the Brightfield Group, which says the CBD market could reach $22 billion by 2022, more is more than the projected recreational cannabis market.Related: New Poll Finds Highest Support Ever for Weed LegalizationBut is CBD medicinal or medical cannabis? Most people take CBD medicinally, not recreationally, with some replacing pharmaceuticals with CBD. Others use it to address conditions for which they never took a prescription, and a growing number use it as preventative medicine.In other words, the distinction between medicinal and medical cannabis is hazy. With more research demonstrating CBD’s effectiveness, cannabidiol could soon be redefined. This is most likely to occur after national legalization — and once Big Pharma becomes more involved.Big Pharma could change the cannabis industry.The American pharmaceutical industry is the biggest industry in the country and it continues to grow. It represents 45 percent of the global pharmaceutical industry, according to Statista. Big Pharma is investing in weed research, a second big reason why medical cannabis could surpass recreational sales. Because pharmaceutical companies are investigating cannabis medicine, CBD could become a more common form of medical marijuana, not just a supplement categorized as recreational.Pharmaceutical companies are putting more resources than ever into CBD research to satisfy the demand for cannabis-wellness. There has already been a breakthrough. Epidiolex in 2018 became the first FDA-approved cannabis-derived medication. It is prescribed to treat two types of epilepsy. FDA reclassified Epidiolex as a substance with a lower likelihood of abuse than recreational cannabis. Though just one drug, Epidiolex has opened the floodgates for other pharmaceutical companies to start exploring medical cannabis.Medical marijuana research is still in its infancy. But in 2018, pharmaceutical companies filed more cannabis patents than ever. Six of the top 10 cannabis patent holders are pharmaceutical companies, according to a recent report. Expect to see many more cannabis medicines available in coming years.Related: The UN Is Moving Toward Ending Decades of International Cannabis ProhibitionCannabis consumer demographics keep shifting.The U.S. baby boomers are the largest generation in American history. There are 76 million baby boomers in the U.S., according to Pew Research, ranging in age from 54 to 73. That is a large segment of the population that is either eligible for Medicare or soon will be.It isn’t a coincidence that seniors are one of the fastest expanding cannabis users. Not only are seniors spending more on marijuana than ever before, but they’re accustomed to spending a lot on medication. A report found that brand name drug prices have almost doubled in nine years.As a result, seniors are more likely to look for less expensive alternatives, like cannabis. Pharmaceutical companies are incentivized more than ever to create medical cannabis products to appeal to their older demographic.An additional factor in coming years is that contemplated changes to global treaties could create an international medical cannabis market, with CBD specifically exempted from international prohibition. This creates the potential for eventually allowing cannabis producers, such as those in Canada projected to eventually glut domestic markets, to export to newly opened markets. The United Kingdom and Thailand recently legalized medical marijuana, and many European countries are in the process of relaxing their laws.For more developed markets with bigger producers, this translates to massive potential for medical marijuana overseas in markets that are far away from recreational legalization.Related: Why Will Health Insurers Reimburse You for Opioids but Not for Medical Marijuana?Will medical cannabis surpass recreational?Recreational cannabis will be huge but increasing interest in medicinal cannabis, global market growth and involvement from Big Pharma could make medical cannabis the larger of the two markets. For this to happen, however, there are a few things that have to change. Specifically, this would require better accessibility to medical cannabis — more doctors, easier applications and more options when it comes to medication targeting specific illnesses — and a better understanding of how we can use CBD medically. Lastly, for the market to really reach its potential, international expansion of the medical cannabis market needs to be legalized.One thing is for certain: The market for cannabis medications will continue to grow as baby boomers come of age, stigma decreases and continuing research confirms the effectiveness of cannabis for many common ailments. Next Article Founder of crypto site Blocklr & Growth Nuts, an organic growth co. Add to Queue Green Entrepreneur provides how-to guides, ideas and expert insights for entrepreneurs looking to start and grow a cannabis business. –shares Opinions expressed by Entrepreneur contributors are their own. Scott McGovern Get 1 Year of Green Entrepreneur for $19.99 We are on the brink of a global medical cannabis boom. April 8, 2019last_img read more

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Solid US Retail Sales Point to Firming Economic Recovery

first_img –shares Solid U.S. Retail Sales Point to Firming Economic Recovery Retail Jack Reed can see the recovery taking hold at his family’s 109-year-old clothing store in Tupelo, Mississippi, with sales buoyed in part by the paychecks tied to a Toyota plant up the road and rising confidence that the jobs are here to stay.As retailers nationwide reported a brisk jump in November sales and optimism about the holiday season, Reed said on Thursday that the gears of the U.S. economy seemed to have finally meshed.”There is just less fear from people who feel like they might lose their jobs … Our shoppers seem more confident than they did a year ago,” said Reed, 63, whose chain of four stores clocked a roughly 10 percent jump in sales from Thanksgiving to this week, compared to the year before.In a rural area that counts Elvis Presley among its native sons, the drop in gasoline prices also was leaving more money in people’s pockets.November’s retail advance showed the holiday shopping season was off to a strong start, and dispelled the gloom from a drop in Black Friday weekend commerce. Black Friday, the day after Thanksgiving, has traditionally been seen as the kickoff for holiday sales, but analysts say consumers have shifted spending through the month and are doing more shopping online.Coupled with strong job reports and signals of upcoming wage growth, the sales data could boost confidence in the durability of the recovery as the Federal Reserve debates when and how fast to raise U.S. interest rates.Retail sales excluding automobiles, gasoline, building materials and food services, increased 0.6 percent last month after rising 0.5 percent in October, the Commerce Department reported. The so-called core retail sales correspond most closely with the consumer spending component of gross domestic product. November’s increase exceeded Wall Street’s expectations for a 0.4 percent gain.It also suggested that consumer spending, which accounts for more than two-thirds of U.S. economic activity, was accelerating in the fourth quarter after slowing in the July-September period.Core November sales were up 4.4 percent from a year earlier, the largest year-over-year increase since early 2012. Over the past 20 years, the average change in December sales is close to the average change in November, and analysts said they expected last month’s momentum to continue.The National Retail Federation said the November result supported its expectation for an overall 4.1 percent jump in holiday season sales – confirming its conclusion that the poor Black Friday showing was a result of a shift in shopping patterns rather than a sign of weakness.Economists at Macroeconomic Advisers boosted their forecast for fourth-quarter economic growth by three-tenths of a percentage point to an annualized rate of 2.4 percent, on the “unexpected strength” in consumer spending. Initial estimates of prior months’ consumer spending were also revised upward.The gains were broad-based. Sales for clothing stores like Reed’s grew a particularly strong 1.2 percentage points over the prior month, while electronics and appliance outlets saw a sizable 0.9 percent gain.Even gasoline stations recorded a better-than-expected result, declining a less-than-anticipated 0.8 percent. Gasoline prices have dropped an average of 67 cents per gallon since the start of the year, saving consumers tens of billions of dollars at the pump.”Perhaps there was an offsetting volume effect, or gas station visitors just spent the extra money on corn nuts, beef jerky and hood ornaments,” RBS Securities economist Guy Berger said.(Reporting by Michael Flaherty; Additional reporting by Howard Schneider and Jason Lange in Washington and Richard Leong in New York; Writing by Howard Schneider; Editing by Paul Simao) Add to Queue The only list that measures privately-held company performance across multiple dimensions—not just revenue. Reuters December 12, 2014center_img Image credit: Reuters | David McNew This story originally appeared on Reuters 3 min read 2019 Entrepreneur 360 List Next Article Apply Now »last_img read more

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Hulu Will Offer Live TV in Early 2017

first_img That talk of Hulu getting into live TV? It’s real.Company chief Mike Hopkins has announced that you’ll see live entertainment, sports and news on the streaming service in early 2017. He didn’t say which networks were involved or what it might cost, but the Wall Street Journal leak had suggested that at least Disney and Fox (including channels like ESPN and FX) were signing on. You’ll hear more about Hulu’s plans over the course of this year, Hopkins says.Hulu is a bit late to the live TV streaming party, as companies like Dish (Sling TV) and Sony (PlayStation Vue) have had a presence for months. However, it has a few advantages. On top of being a veteran in the on-demand TV world, it can point to major TV providers (including Disney and Fox) that have direct stakes in the company — they have a vested interest in Hulu’s success. While those networks still make a big chunk of their revenue from people watching conventional TV, they may steer you toward Hulu if you’ve already cut the cord.There’s more on the way, too. Hulu has revealed that it’s getting into documentaries, beginning with the exclusive U.S. streaming rights to Ron Howard’s upcoming documentary on the first half of The Beatles’ career (tentatively titled The Beatles: Eight Days a Week). You’ll have to wait until the fall to see it, but it’s evident that Hulu wants to rival Netflix’s variety and prevent the next Making a Murderer from going to its competition. 2 min read Next Article Learn from renowned serial entrepreneur David Meltzer how to find your frequency in order to stand out from your competitors and build a brand that is authentic, lasting and impactful. Jon Fingas May 4, 2016 Hulu Image credit: Paul Zimmerman/Getty Images for Hulucenter_img –shares Hulu Will Offer Live TV in Early 2017 This story originally appeared on Engadget Add to Queue Fireside Chat | July 25: Three Surprising Ways to Build Your Brand Enroll Now for $5last_img read more

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Salsify Announces New GDSN Data Pool Designed for the Digital Shelf

first_imgSalsify Announces New GDSN Data Pool Designed for the Digital Shelf PRNewswireJuly 12, 2019, 2:44 pmJuly 12, 2019 GDSNMarketing Technology NewsMaster Data ManagementNewsProduct experience managementSalsify Previous ArticleRackspace and Tech Mahindra Partner to Lead with New Go-To-Market StrategyNext ArticleQualtrics Ranked Top 10 Most Innovative Company in 2019 GRIT Report Brand Manufacturers Can Manage and Deliver Content for Retail and Ecommerce Channels from One PlatformSalsify, a product experience management (PXM) platform that helps brands win on the digital shelf, announces a new data pool for GS1’s Global Data Synchronization Network (GDSN). This expanded capability will allow IT, Master Data Management (MDM), ecommerce, trade, and marketing teams to manage and share their product data with retailers and distributors across the GDSN from a single platform.As the only PXM platform with both product information management (PIM) capabilities and a native data pool that covers GS1’s complete Global Data Dictionary (GDD), Salsify now provides customers with an end-to-end solution for managing and transmitting product content for both traditional wholesale – where GDSN has been vital – and ecommerce channels. The Salsify platform unites the work of all teams involved in bringing products to market, streamlining processes, confirming responsibilities and handoffs through integrated workflows, and providing a single source of truth for all product data. This unified solution results in:Marketing Technology News: UiPath Named a Leader in the 2019 Gartner Magic Quadrant for Robotic Process AutomationFaster item setup: The unification of both logistical and top-off marketing data in one platform significantly reduces the time it takes to bring a new product to market.Content refresh at the speed of commerce: Optimizing for SEO, publishing new packaging variations, adding more engaging media such as 360 spins and lifestyle images, and reacting to consumer feedback in ratings and reviews all require frequent updates to product detail pages and product content. Bringing ecommerce teams into the loop with Salsify’s unified solution ensures that rich content that changes frequently can go through the same GDSN that supply chain data does.Compliance with confidence: Salsify maintains the complex requirements for each region and target market, enabling customers to stay compliant with global retailer requirements with a single data pool. The platform’s readiness reports and workflows immediately surface violations and users can assign tasks for remediation.Marketing Technology News: JumpCrew Announces Inaugural Conference “JumpCon: The Digital Sales Transformation Summit”“Our customers have pushed us to unite their offline and online product content processes to serve the need for accurate, complete, and differentiated product experiences everywhere on the digital shelf,” said Jason Purcell, co-founder and CEO of Salsify. “Adding a GDSN data pool to our platform helps bring to life GS1’s original vision of efficient and automated exchange of continuously refreshed product data across the globe.”The Salsify for GDSN data pool is currently in the certification process with GS1. Certification is expected this quarter, with immediate availability thereafter.Marketing Technology News: Valassis’ Marketing Technology Platform Earns Tech Awardlast_img read more

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New molecular switch may help develop sophisticated photomedications

first_imgReviewed by James Ives, M.Psych. (Editor)Oct 11 2018Light-activated switches are too small to be seen by the naked eye, but the molecular systems are hard at work in research related to drug design, adaptive materials and data storage. To unlock the promise of new generations of medical therapies and memory systems, researchers must first overcome the drawbacks of the microscopic devices that can be difficult to produce and lack versatility.Researchers at Dartmouth College have developed a new molecular switch based on the hydrazone functional group that combines the most important properties of the current class of light-activated switches and solves many of the problems associated with them. The newly-developed molecule is easy to make, simple to work with, shows “on-off” fluorescence emission toggling, and can be used to write, read and erase information in both the liquid and solid state.Looking into the future, switches like these may potentially be used for the development of sophisticated photomedications that deliver drugs with cellular-level precision. In years to come, hydrazone switches might also lead to the development of high-density memory devices with the volume of a speck of a dust.As detailed in the Journal of the American Chemical Society, Dartmouth’s hydrazone system, “packs most, if not all, the desired, targeted and sought-after traits from photochromic compounds.””This is a switch that can do it all,” said Ivan Aprahamian, an associate professor of chemistry and head of the research team at Dartmouth. “What we developed is a new tool that combines all the good properties of known switches without their side effects, and in a simple, straight-forward design.”Similar to flipping a physical switch, photochromic switches rely on lights of different wavelengths to move molecules between the “on” and “off” positions. The fluorescent feedback produced during the switching process can be used to store and read huge amounts of data at microscopic scale and even provide signals about where a medication is being delivered after the drug enters into a patient’s body, an important tool for drug targeting.Related StoriesCharacterizing and Isolating (Bio)macromolecular Structures using MALSExperts discuss 5G health risks as network switches on in the UKComplement system shown to remove dead cells in retinitis pigmentosa, contradicting previous researchTo toggle the switch in the Dartmouth study, researchers used a “blue light” operating at the same 450 nm wavelength of a laser pointer to write the information by activating the switch. A second 365 nm ultraviolet wavelength was used to erase the information by turning the switch off.In the paper, the researchers demonstrated that the switch works in both water and fetal bovine serum buffer–a frequently used bio-medium–confirming that the molecular system can be useful as a drug delivery tool.In addition to performing well in solution, the researchers found that the hydrazone switch also works on solid-state films. Molecules that go through large structural changes usually do not operate in solid state without complex manipulation. This added functionality allows it to be used effectively for data storage.”Such an on-off fluorescence response in both solution and solid state for photochromic compounds is highly unusual,” said Baihao Shao, a PhD student at Dartmouth and the first author of the study.The team was able to use both single-photon and two-photon light sources to operate the new switch. The near infrared, two-photon system allows the light to penetrate tissue deeper and makes it safer for use with humans. Two-photon activation also allows for 3D microscopy techniques that are important for advanced data storage.The research paper notes that the hydrazone switch has a half-life of 75 years in solution at room temperature. In solid state, the switch’s memory could be indefinite. Such stability is another key feature that adds to its overall functionality for long-term data storage.”We are extremely excited by the results as well as the reception it is getting from the scientific community. Based on these and yet unpublished results, we feel that this technology has the promise to be truly transformative,” said Aprahamian.During the experiment, some erasure did occur during reading as the excitation light also results in slow switching, creating a challenge that the researchers are working to minimize. Source:https://news.dartmouth.edu/last_img read more

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Whats the best time of the day to lose weight

first_imgResearchers have found that late afternoons and early evenings are the best time to lose weight as the metabolic rates are the highest around that time. The results of the study titled ‘Human Resting Energy Expenditure Varies with Circadian Phase’, is published in the latest issue of the journal Current Biology. For this study the seven participants (aged 38 to 69 years) were made to stay inside a special laboratory with no clues about time of the day for 37 days. They were not given access to windows, phones, clocks or the internet. Each night the bedtime for the participants was shifted by four hours. It was similar to be travelling across four time zones to the west each day for three continuous weeks. Their sleep wake cycle as well as food and exercise was also tightly regulated by the researchers. This helped the researchers alter the body’s circadian rhythm or clock. Now metabolism and metabolic rates at different times of the day was analyzed. The study results revealed that 10 percent extra calories could be burnt in the late afternoons and early evenings as the metabolic rates are the highest around that time. The body temperatures were lowest around middle of the night and highest in the late afternoons and early evenings.According to the team of researchers, this study shows why shift workers tend to be irregular in their sleep and eating schedules and tend to gain weight. Shift workers are at a greater risk of diabetes, heart disease, obesity, cognitive problems as well as cancers, as has been seen in several previous studies. The researchers explain that the body’s circadian clock could be governing the metabolism and metabolic rates.Related StoriesSleep quality and fatigue among women with premature ovarian insufficiencyDiet and nutrition influence microbiome in colonic mucosa’Traffic light’ food labels associated with reduction in calories purchased by hospital employeesKirsi-Marja Zitting, of the Division of Sleep and Circadian Disorders at Brigham and Women’s Hospital and Harvard Medical School in Boston, one of the team members said that they were surprised that same exercises and exertions at one time of the day worked at burning calories differently than when performed at a different time of the day. “Because they were doing the equivalent of circling the globe every week, their body’s internal clock could not keep up, and so it oscillated at its own pace,” Zitting said.Jeanne Duffy, co-author of the study and an associate professor of medicine at Harvard Medical School and a neuroscientist at Brigham and Women’s Hospital, added that this study showed that it was not only what we ate and how much we exercised that determined how many calories we would burn but the “when” was also very important. “Regularity of habits such as eating and sleeping is very important to overall health,” she said. She explained that 10 percent extra calories could be burnt if exercised in the later afternoons and early evenings compared to middle of the night. It means that a person can burn 130 extra calories with no added effort, she said. She went on to explain that if this was happening each day, the resultant accumulative effects can also be estimated. It is thus important to keep the body’s internal clock in synchrony with the external environment for good heath she said. “Regularity is really important,” she said.As the next step the team would connect the effects of sleep time, duration and regularity and its effect on weight gain. Source:https://www.cell.com/current-biology/fulltext/S0960-9822(18)31334-4center_img By Dr. Ananya Mandal, MDNov 8 2018Image Credit: WindNight / Shutterstocklast_img read more

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UTA bioengineers aim to develop new method to repair vaginal prolapses in

first_img Source:https://www.uta.edu/news/releases/2019/01/Yi-Hong-NIH-vaginal-prolapse.php Reviewed by James Ives, M.Psych. (Editor)Jan 24 2019A team of bioengineers at The University of Texas at Arlington is working to develop a method that will allow physicians to repair vaginal prolapses while they are in their early stages, potentially avoiding surgery and other complications.Hong, an associate professor in UTA’s Bioengineering Department, is leading an interdisciplinary team that will use a five-year, $1.9 million grant from the National Institutes of Health to develop a new method of treating a vaginal prolapse before the vagina completely detaches, which could prevent complications and improve the quality of life of thousands of women.Hong’s UTA colleagues Kytai Nguyen, Liping Tang and Jun Liao, along with UT Southwestern urologist Phillippe Zimmern are co-principal investigators on the project. Vaginal prolapse is a condition affecting almost 3 percent of U.S. women, according to the Office on Women’s Health. In a prolapse, the pelvic floor muscles weaken and tear, allowing the vagina to stretch or expand and protrude on surrounding organs and structures. Treatment usually involves surgical implantation of mesh to repair the muscles, but the mesh often leads to severe complications that require extended recovery time and cause discomfort.Related StoriesTransobturator sling surgery shows promise for stress urinary incontinenceSchwann cells capable of generating protective myelin over nerves finds researchMathematical model helps quantify metastatic cell behaviorHong and his team are developing a strong, bioactive bioadhesive that is strong and bioactive to reattach the pelvic floor muscles early, before they detach completely, and stop further tearing while the body repairs the affected muscles.”A lot of women suffer from vaginal prolapse and it really affects their quality of life. Hopefully, our research will help women and ease their discomfort,” Hong said. “It is difficult to repair a full muscle tear, but if a prolapse is detected early, we can glue the two edges together while they are still partially attached and prevent further damage. Because it is bioactive, the adhesive will allow the body to rejuvenate naturally, and there will be far less discomfort for the patient.” Hong’s research is an example of health and the human condition, one of four themes of UTA’s Strategic Plan 2020, and of the ways that the University is making an impact on the community, said Michael Cho, chair of the Bioengineering Department.”This is a condition that affects women of all ages, and Dr. Hong and his team have a chance to make its treatment easier and less intrusive for those women. His ability to apply knowledge and techniques from previous research, as well as the strengths from the interdisciplinary team of investigators, will lead to success,” Cho said.last_img read more

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Men Notice Messes As Much As Women Heres Why They Dont Clean

first_imgOn a typical day, men spend a third as much time cleaning as women. Does that make women beacons of cleanliness, while men are genetically unable to see the messiness in their midst? This myth is a common explanation for why men don’t do as much housework as women. Men walk into a room and apparently can’t see the dust bunnies gathering on the floor or the piles of laundry stacked up on the couch.These Sharks Were Too Busy to Notice a Bigger Predator Watching ThemThe unexpected twist at the end of this feeding frenzy delighted scientists.Credit: NOAA Office of Ocean Exploration and Research, Windows to the Deep 2019Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Headbutting Tiny Worms Are Really, Really Loud00:35关闭选项Automated Captions – en-US facebook twitter 发邮件 reddit 链接https://www.livescience.com/65875-why-men-do-less-housework.html?jwsource=cl已复制直播00:0002:2802:28  It lets men off the hook for not doing their fair share of the household cleaning. But in a recent study we show that men aren’t dirt-blind — they can see mess just as well as women. They are simply less severely penalized for not keeping their spaces neat and tidy. Chore inequality Despite massive gains in education and employment, women still shoulder a larger share of the housework than men. Women today spend, on average, roughly an hour and 20 minutes per day cooking, cleaning and doing laundry. About a third of that is just spent cleaning. Men, on the other hand, spend about half an hour performing these duties — and only 10 minutes scrubbing and tidying. This household chore inequality is evident over time, across professions and even when women work longer hours and make more money. Even in Sweden, where government policies are strongly geared toward promoting gender equality, women do more housework. Swedish women do two times as much daily housework than men even though women are much more likely to work full-time than in other countries. Naturally, the more time spent on chores, the less a woman has to spend on other activities like sleep, work and leisure. The same mess In our study, which was recently published in Sociological Methods and Research, we asked 327 men and 295 women of various ages and backgrounds to assess a photo of a small living room and kitchen area. By random assignment, some participants rated a photo of the room looking cluttered — dirty dishes on the counter, clothing strewn about — while others examined a much tidier version of the same room. All participants looked at the one photo they were given and then rated how messy they thought it was and how urgently it needed cleaning. The first thing we wanted to know was whether men and women respondents rated the rooms differently. Contrary to popular lore, men and women saw the same mess: They rated the clean room as equally clean and the messy room as equally messy. Differing expectations So if “dirt blindness” isn’t to blame, why do women do more housework? One argument is that social expectations are different for men and women. Women may be judged more harshly for having a less-than-spotless home, and women’s awareness of these expectations may motivate them to do more. We tested this idea by randomly telling participants that the photo they were looking at depicted either “John’s” or “Jennifer’s” living space. Then we asked them to rate Jennifer’s or John’s character — how responsible, hardworking, neglectful, considerate and likable they were — based on the cleanliness of their home. We also asked participants to assess the extent to which she or he might be judged negatively by unexpected visitors — extended family, bosses and friends — and how much responsibility they believed Jennifer or John would bear for housework if they were working full-time and living alone, working full-time and married with children, or a married, stay-at-home parent. This is where things got interesting. Participants rated the photos differently depending on whether they were told that a woman or a man lived there. Notably, respondents held higher standards of cleanliness for Jennifer than they did for John. When they were told the tidy room belonged to Jennifer, participants — regardless of gender — judged it less clean and more likely to inspire disapproving reactions from guests than when the same exact room was John’s. We’ve all heard ‘men are lazy’ Still, we did find that both men and women pay a large penalty for having a cluttered home. Compared to their tidier counterparts, both Jennifer and John received substantially more negative character ratings and were expected to garner much more negative judgments from visitors. Interestingly, John’s character was rated more negatively than Jennifer’s for having a messy home, reflecting the common stereotype that men are lazy. Yet participants did not believe John would be any more likely than Jennifer to suffer negative judgment from visitors, which suggests that the “men are lazy” stereotype does not disadvantage them in a socially meaningful way. Finally, people were more likely to believe that Jennifer would bear primary responsibility for cleaning, and this difference was especially large in the hypothetical scenario in which she or he is a full-time working parent living with a spouse. That people attribute greater responsibility for housework to women than men, even regardless of their employment situation, suggests that women get penalized more often for clutter than men do. Judge not People hold women to higher standards of cleanliness than men, and hold them more responsible for it. Some women may internalize or embrace such standards. But for many, it is unlikely a love of cleaning but rather a fear of how mess will be perceived that is the real problem — and one possible reason why many women frantically clean their home before unexpected visitors arrive. The good news is that, with enough collective willpower, old-fashioned social expectations can be changed. We could start by thinking twice before judging the state of someone’s home, especially our own. This article is republished from The Conversation under a Creative Commons license. Read the original article. Sarah Thebaud, Associate Professor, Sociology, University of California, Santa Barbara; Leah Ruppanner, Associate Professor in Sociology, University of Melbourne, and Sabino Kornrich, Assistant Professor of Sociology, Emory Universitylast_img read more

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Laidoff expat bankers struggle to find jobs in Hong Kong

first_img Tags / Keywords: World 09 Jul 2019 Hong Kong singer-activist urges U.N. rights body to defend territory HONG KONG: For years, Hong Kong was a hotspot with plum jobs for overseas bankers as global firms hired aggressively. But many recently laid-off bankers in the city are finding that cost-cutting and a demand for Mandarin speakers have diminished the opportunities for expats in Asia’s financial hub.After Deutsche Bank AG announced plans for wide-ranging cuts this week, many employees worldwide are facing the challenge of job-hunting in a shrinking market. For foreign staff losing positions in Hong Kong, it could be harder than most.Other international firms such as Nomura Holdings Inc. have also cut jobs in Hong Kong. At the same time, the city’s famously expensive living costs, including some of the world’s highest rents, mean that even senior bankers need to find new jobs fast in order to stay.The upshot? Expat bankers who lost their jobs and want to remain in Hong Kong often have to consider lower-paying options or demotions. Some with longer-running ties to the city are looking at switching careers, weighing everything from consulting to cryptocurrency outfits.During the global financial crisis of 2008, Asian banks and local Chinese firms hired those who had been laid off by foreign players, said Will Glover, Hong Kong-based managing director for recruitment firm Macdonald & Co. That’s less likely this year and some of those taking on new jobs may have to take pay cuts, he said.”You get that volume of people anywhere into a market at one time and inevitably a lot of people will leave the market altogether,” Glover said. “There will not be enough opportunities to absorb all that supply.”While global banks are ramping up their focus on China, more of them are looking for people with language skills and networks on the Chinese mainland. That could help Deutsche Bank staff from around the world who are Chinese citizens, and who have been sending resumes seeking jobs back home or at Chinese banks. But for Westerners in Hong Kong, the prospects look tougher.Looking to StayA senior banker in Hong Kong who is in his 50s and was laid off from a European investment bank earlier this year said he would like to continue to live in the city, where his children go to school.But he expects it to be hard to find a top job because banks are moving people internally or hiring more people locally. His monthly rent is about HK$100,000 ($12,800), making it essential to find a job soon if he decides to stay.It’s a dilemma that many others are grappling with. One European banker laid off from a top Asian bank said he took a holiday and is now pondering working in a startup or even moving out of Hong Kong after 20 years.Deutsche Bank’s website until Wednesday said it had more than 1,200 people in Hong Kong, although that statistic has since been removed. The bank has cut about half its equities staff in Asia and plans to reduce the group by another 25% within a month, a person familiar with the matter said earlier this month. Deutsche Bank didn’t comment on the size of its layoffs in Hong Kong.A Deutsche Bank employee in Hong Kong, recently laid off, said many of her colleagues plan to stay in Hong Kong and are looking at positions in banking, family offices, or asset management. She’s hoping to use her background in compliance for another job in finance.One former Deutsche Bank employee, Su Zhu, who worked at the firm in Hong Kong until 2012 and now runs a Singapore foreign exchange and cryptocurrency fund called Three Arrows Capital, said that over the past year many bankers have gone into the crypto industry.Foreign banks can now choose from a widening pool of young professionals raised in Hong Kong, who speak multiple languages, know Chinese culture, have trained overseas and don’t require expensive relocation packages. That makes it harder for foreign bankers currently in the city, as well as junior professionals attempting to move from overseas, to find new positions in Hong Kong.A British equities trader who lost his job at an American investment bank this year said he had spent almost four months interviewing at banks and hedge funds with no luck. He lost one position to a local candidate 10 years his junior, and is now considering leaving.Expatriate executives in Hong Kong earn $276,417 a year on average, including benefits, according to a May report by consultancy ECA International, which analyzed salaries from financial and non-financial firms.Pay ScalesAverage pay scales lagged Japan, China and India, although affordable domestic help and a work-friendly visa system for trailing spouses help make Hong Kong attractive. But Hong Kong also topped a recent Deutsche Bank global ranking for the most expensive monthly rents on a two-bedroom apartment, and ranked 39th for disposable income after rent.Senior expats have tended to live in expensive places and send their children to international schools, living off base salaries and saving bonuses, said Benjamin Quinlan, chief executive officer of financial-services consultancy Quinlan & Associates in Hong Kong.”The expat’s side of things is going to be significantly harder,” Quinlan said. “A lot of people are going to have to take down their expectations, even get demoted and really take any opportunity they can really find, as opposed to waiting out in the market for a magic position to come up again because it will not.” – Bloomberg {{category}} {{time}} {{title}} After Deutsche Bank AG announced plans for wide-ranging cuts this week, many employees worldwide are facing the challenge of job-hunting in a shrinking market. Corporate News 08 Jul 2019 Deutsche Bank careers curtailed with an envelope, a hug and a cab ridecenter_img Related News Related News Business News 09 Jul 2019 What Deutsche bank employees are saying about the 18,000 global job cuts Bankinglast_img read more

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Air Marshal RKS Bhadauria shares his experience of flying a Rafale jet

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